Do atypical antipsychotics promote neurogenesis as a class effect?

نویسندگان

  • Mark Agius
  • Karandeep Singh Nandra
چکیده

It has been reported that some atypical antipsychotics promote neurogenesis in the hippocampus and possibly in the frontal cortex. Atypical antipsychotics are a heterogeneous group of drugs. Hence the question arises as to whether neurogenesis is a class effect which relates to them all. We here present a literature search which we have carried out to establish this.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The differences between typical and atypical antipsychotics: the effects on neurogenesis.

Recently, the pharmacological division between typical and atypical antipsychotics has been called into question. New evidence, however, continues to emerge showing differences between these two classes of drugs. Hence typical and atypical antipsychotics are clearly different classes of drugs, as evidenced by their actions, mechanisms, effects and side effects. The most recently investigated fi...

متن کامل

مقایسه مصرف آنتی‌سایکوتیک‌های تیپیک و آتیپیک در ایجاد علایم وسواسی بیماران مبتلا به اسکیزوفرنیا

AbstractObjectives: The effects of typical and atypical antipsychotics on inducing obsessive-compulsive symptoms in patients with schizophrenia were compared in this study. Method: In a comparative-descriptive study 64 patients with schizophrenia (32 patients in typical antipsychotic group and 32 patients in atypical antipsychotic group) were investigated. All patients with a confirmed diagnosi...

متن کامل

The atypical antipsychotics quetiapine, risperidone and ziprasidone do not increase insulin release in vitro.

OBJECTIVE In the light of the recent finding that the atypical antipsychotics clozapine and olanzapine have a stimulatory effect on basal insulin release in vitro, the influence on insulin release of three other atypical agents; quetiapine, risperidone and ziprasidone, was examined. METHODS The effect of each atypical antipsychotic in a concentration of 10(-6) M was investigated on both basal...

متن کامل

Second Messenger Systems, Genes, Neurogenesis, and Mood Disorders

Most important, antidepressants do not work as quickly or as effectively as the original monoamine hypothesis would suggest. Monoamine action also does not explain much of the clinical activity of diverse mood stabilizers (lithium [Eskalith, Lithobid], valproic acid [Depakote, Depakene], carbamazepine [Carbatrol, Tegretol]), and some atypical antipsychotics. In addition, the monoamine theory fa...

متن کامل

The effects of antipsychotics on the brain: what have we learnt from structural imaging of schizophrenia?--a systematic review.

Despite a large number of neuroimaging studies in schizophrenia reporting subtle brain abnormalities, we do not know to what extent such abnormalities reflect the effects of antipsychotic treatment on brain structure. We therefore systematically reviewed cross-sectional and follow-up structural brain imaging studies of patients with schizophrenia treated with antipsychotics. 30 magnetic resonan...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Psychiatria Danubina

دوره 24 Suppl 1  شماره 

صفحات  -

تاریخ انتشار 2012